As Caine’s progeny resumed their foul ways, as the Antediluvian—those who had been Embraced before the Great Flood—preyed once more upon man without fear of retribution, God watched, but He upheld the Covenant. Pride, envy, wrath, gluttony, lust and avarice blossomed like black weeds in the hearts of those who fell under the sway of the Kindred and soon the Earth was no different than it had been before; worse even. As cities sprang up across the globe and every civilization became a playground for the spawn of Caine, they Embraced mortals at will, damning them with their own cursed Blood and spreading their influence into every corner of the world. Centuries passed and nations rose and fell, but the corrupt touch of vampires was always felt. Even during the creatures’ most difficult nights, when the Inquisition was at its righteous height, the shadowy undead continued to play their games and bring as many mortals as was prudent into their service. This was not the world God had hoped to see rise from the flotsam of the Great Flood.

— Wormwood